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Elsevier BV

Member ID: https://id.crossref.org/member/78 · Prefix: 10.3816

Publisher information

Crossref member ID 78
DOI prefix 10.3816
Publisher name Elsevier BV
Other registered names Elsevier BV, Elsevier - Biophysical Society, American Dental Association, Elsevier - Ambulatory Pediatric Associates, Elsevier - Institution of Chemical Engineers, Elsevier - Academic Press, Social Science Electronic Publishing, Elsevier - Colegio Nacional de Opticos-Optometristas de Espana, Canadian Opthalmological Society, Elsevier - American Society for Experimental Neurotherapeutics, Elsevier - Wilderness Medical Society, Elsevier- Spektrum Akademischer Verlag, Elsevier - Medicine Publishing Company, Elsevier - Central Mining Institute, Elsevier - Mosby, Journal of Bioresources and Bioproducts, Elsevier (Society for Range Management), Elsevier - American Society for Investigative Pathology, Elsevier - International Federation of Automatic Control (IFAC), Elsevier - CIG Media Group LP, Elsevier - Ediciones Doyma, Woodhead Publishing, Elsevier, American College of Chest Physicians, Sociedad Argentina de Radiologia, Elsevier - Mayo Clinic Proceedings, Farmacia Hospitalaria, Elsevier- Hanley and Belfus Inc., Elsevier- Churchill Livingstone, Elsevier - WB Saunders, American Pharmacists Association, Elsevier - Urban & Fischer Verlag, American Association for Thoracic Surgery
Place / location Amsterdam, NX, Netherlands

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#TitleAuthorsJournal / SourcePublishedMetadata DepositedTypeCitationsDOI
1Treatment of Unfit Patients With Acute Myeloid Leukemia: A Still Open Clinical ChallengeFelicetto FerraraClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1510.3816/clml.2011.n.001
2Distinctive Clinical and Histological Features of Waldenström's Macroglobulinemia and Splenic Marginal Zone LymphomaLuca Arcaini, Marzia Varettoni, Emanuela Boveri, Ester Orlandi, Sara Rattotti, Silvia Zibellini, Michele Merli, Marco Lucioni, Silvia Rizzi, Manuel Gotti, Lucia Morello, Cristiana Pascutto, Marco PaulliClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article2410.3816/clml.2011.n.020
3High-Throughput Genomic Analysis in Waldenström's MacroglobulinemiaStéphanie Poulain, Esteban Braggio, Christophe Roumier, Rachid Aijjou, Natacha Broucqsault, Sylvie Galiègue-Zouitina, Salomon Manier, Valérie Soenen, Olivier Nibourel, Patrick Duthilleul, Rafael Fonseca, Xavier LeleuClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article2110.3816/clml.2011.n.021
4Prognostic Relevance of Immunohistochemical Subclassification of Diffuse Large B-Cell Lymphoma in Two Prospective Phase III Clinical TrialsNazik Rayman, King H. Lam, Bronno van der Holt, Clara Koss, Dennis Veldhuizen, Leo M. Budel, Andries H. Mulder, Leo F. Verdonck, Ruud Delwel, Daphne de Jong, Gustaaf W. van Imhoff, Pieter SonneveldClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1010.3816/clml.2011.n.003
5Analysis of 31 Cases of Primary Breast Lymphoma: The Effect of Nodal Involvement and Microvascular DensityShu Zhao, Qing-Yuan Zhang, Wen-Jie Ma, Ming-Hui Zhang, Wen-Zhou Sun, Hong-Bin Li, Xiao-San Zhang, Wen-Yu Di, Xiao-Chuan WangClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1910.3816/clml.2011.n.004
6Matrix Metalloproteinase-8 Is Overexpressed in Waldenström's Macroglobulinemia Cells, and Specific Inhibition of this Metalloproteinase Blocks Release of Soluble CD27Yangsheng Zhou, Xia Liu, Lian Xu, Hsiuyi Tseng, Yang Cao, Jingrui Jiang, Bryan T. Ciccarelli, Guang Yang, Christopher J. Patterson, Zachary R. Hunter, Steven P. TreonClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1710.3816/clml.2011.n.041
7Heterogeneity of Histological Transformation Events in Waldenström's Macroglobulinemia (WM) and Related DisordersR G Owen, A G Bynoe, A Varghese, R.M. de Tute, A C RawstronClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article2710.3816/clml.2011.n.042
8Novel Diagnostic Approaches in Bing-Neel SyndromeK. Ina Ly, Florian Fintelmann, Reza Forghani, Pamela W. Schaefer, Ephraim P. Hochberg, Fred H. HochbergClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article3210.3816/clml.2011.n.043
9Efficacy and Safety of Pegylated Liposomal Doxorubicin in Combination With Bortezomib for Multiple Myeloma: Effects of Adverse Prognostic Factors on OutcomeJoan Bladé, Pieter Sonneveld, Jesús F. San Miguel, Heather J. Sutherland, Roman Hajek, Arnon Nagler, Andrew Spencer, Tadeusz Robak, Keith C. Lantz, Sen H. Zhuang, Jean-Luc Harousseau, Robert Z. OrlowskiClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article3510.3816/clml.2011.n.005
10CD30-Positive EBV–Associated Diffuse Large B-Cell Lymphoma Occurring After Immunosuppressive Therapy for T-Cell Prolymphocytic LeukemiaAhmad Alduaij, Diana O. Treaba, Eric S. WinerClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article410.3816/clml.2011.n.009
11Report From the Sixth International Workshop on Waldenström's MacroglobulinemiaSteven P. Treon, Giampaolo Merlini, Enrica Morra, Christopher J. Patterson, Marvin J. StoneClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1210.3816/clml.2011.n.010
12IgM Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Waldenström's Macroglobulinemia (SWM)Robert A. Kyle, Angela Dispenzieri, Shaji Kumar, Dirk Larson, Terry Therneau, S. Vincent RajkumarClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article2710.3816/clml.2011.n.011
13Immunohistochemical Phenotyping of Plasma Cells in Lymphoplasmacytic Lymphoma/Waldenström's Macroglobulinemia is Comparable to Flow Cytometric TechniquesMatthew T. Howard, Janice Hodnefield, William G. MoriceClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1410.3816/clml.2011.n.018
14CD138 Expression Helps Distinguishing Waldenström's Macroglobulinemia (WM) From Splenic Marginal Zone Lymphoma (SMZL)Marie-Christine Kyrtsonis, Georgia Levidou, Penelope Korkolopoulou, Efstathios Koulieris, Vassiliki Bartzi, Dimitrios Maltezas, Gerassimos A. Pangalis, Christina Kalpadakis, Maria Dimou, George Georgiou, Theodoros P. Vassilakopoulos, Maria K. Angelopoulou, Vassilis Salpeas, Panagiotis Tsaftaridis, Efstratios Patsouris, Panayiotis Panayiotidis, Tatiana K. TzenouClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article2310.3816/clml.2011.n.019
15Phase I Study of Atacicept in Relapsed/Refractory Multiple Myeloma (MM) and Waldenström's MacroglobulinemiaJean-François RossiClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1410.3816/clml.2011.n.031
16Autologous Stem Cell Transplantation as a Care Option in Waldenström's MacroglobulinemiaSaad Usmani, Rachel Sexton, John Crowley, Bart BarlogieClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1710.3816/clml.2011.n.032
17Tanespimycin as Antitumor TherapyMeletios-Athanassios Dimopoulos, Constantine S. Mitsiades, Kenneth C. Anderson, Paul G. RichardsonClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article3810.3816/clml.2011.n.002
18Novel M-Component Based Biomarkers in Waldenström's MacroglobulinemiaXavier Leleu, Efstathios Koulieris, Dimitrios Maltezas, Raphael Itzykson, Wanling Xie, Salomon Manier, Remy Dulery, Eilleen Boyle, Jordan Gauthier, Stéphanie Poulain, Tzenou Tatiana, Panayiotis Panayiotidis, Arthur R. Bradwell, Stephen Harding, Veronique Leblond, Marie-Christine Kyrtsonis, Irene M. GhobrialClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article2110.3816/clml.2011.n.039
19Post-Treatment Bone Marrow Residual Disease > 5% by Flow Cytometry Is Highly Predictive of Short Progression-Free and Overall Survival in Patients With Waldenström's MacroglobulinemiaR García-Sanz, EM Ocio, A Caballero, R J P Magalhães, J Alonso, L López-Anglada, T Villaescusa, N Puig, J M Hernández, J Fernández-Calvo, A Aguilar, A Martín, R López, B Paiva, A Orfao, B Vidriales, J F San-Miguel, D. del CarpioClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article2010.3816/clml.2011.n.040
20Key Role of MicroRNAs in Waldenström's Macroglobulinemia PathogenesisAntonio Sacco, Patricia Maiso, Abdelkareem Azab, Feda Azab, Yong Zhang, Yang Liu, Hai T. Ngo, Brittany Morgan, Phong Quang, Ghayas Issa, Irene M. Ghobrial, Aldo M. RoccaroClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article210.3816/clml.2011.n.022
21Jak/Stat Pathway in Waldenström's MacroglobulinemiaLucy S. Hodge, Stephen M. AnsellClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1210.3816/clml.2011.n.023
22Expression of CCL3 by Neoplastic Cells in Patients with Waldenström's Macroglobulinemia: An Immunohistochemical Study in Bone Marrow Biopsies of 67 PatientsEvangelos Terpos, Anna Tasidou, Evangelos Eleftherakis-Papaiakovou, Dimitrios Christoulas, Maria Gavriatopoulou, Maria Gkotzamanidou, Maria Roussou, Efstathios Kastritis, Theodora Papadaki, Meletios-Athanassios DimopoulosClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1010.3816/clml.2011.n.024
23The Bone Marrow Niche in Waldenström's MacroglobulinemiaIrene M. Ghobrial, Yong Zhang, Yang Liu, Hai Ngo, Feda Azab, Antonio Sacco, Abdelkareem Azab, Patricia Maiso, Brittany Morgan, Phong Quang, Ghayas Issa, Aldo RoccaroClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article310.3816/clml.2011.n.025
24Can ISSWM Be Used for Making Treatment Decisions?Pierre Morel, Giampaolo MerliniClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article210.3816/clml.2011.n.026
25The Impact of Advanced Age According to IPSSWM Cut-Off on the Outcome of Symptomatic and Asymptomatic Waldenström's Macroglobulinemia at DiagnosisF Ricci, A Tedeschi, E Vismara, M Montillo, M Nichelatti, M Varettoni, M Lazzarino, E Morra, A GrecoClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1110.3816/clml.2011.n.027
26Copy Number Variations of EphA3 Are Associated With Multiple Types of Hematologic MalignanciesMing Guan, Li Liu, Xiaosu Zhao, Qi Wu, Bo Yu, Yong Shao, Hong Yang, Xinrong Fu, Jun Wan, Wei ZhangClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article3110.3816/clml.2011.n.006
27Augmented Hyper-CVAD Based on Dose-Intensified Vincristine, Dexamethasone, and Asparaginase in Adult Acute Lymphoblastic Leukemia Salvage TherapyStefan Faderl, Deborah Ann Thomas, Susan O'Brien, Farhad Ravandi, Guillermo Garcia-Manero, Gautam Borthakur, Alessandra Ferrajoli, Srdan Verstovsek, Mohamed Ayoubi, Michael Rytting, Jennie Feliu, Hagop M. KantarjianClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article5510.3816/clml.2011.n.007
28Large Vessel (Takayasu's) Arteritis in a Patient With Myelodysplastic Syndrome: Is There a Common Pathogenesis?Matan J. Cohen, Anat Shyman, Martine Klein, Aryeh Ben-Yehuda, Alan Rubinow, Reuven Or, Neta GoldschmidtClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1710.3816/clml.2011.n.008
29Treatment of IgM-Associated AL Amyloidosis With the Combination of Rituximab, Bortezomib, and DexamethasoneGiovanni Palladini, Andrea Foli, Paola Russo, Paolo Milani, Laura Obici, Francesca Lavatelli, Giampaolo MerliniClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article3510.3816/clml.2011.n.033
30IgM Amyloidosis: Clinical Features in Therapeutic OutcomesMorie A. Gertz, Francis K. Buadi, Suzanne R. HaymanClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article3110.3816/clml.2011.n.034
31Update in Indolent Non-Hodgkin Lymphoma (NHL): Paradigm for Waldenström's Macroglobulinemia (WM)Annalisa Chiappella, Chiara Ciochetto, Lorella Orsucci, Umberto VitoloClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article510.3816/clml.2011.n.035
32Prognostication of the High-Risk WM PatientEfstathios Kastritis, Maria Gavriatopoulou, Marie-Christine Kyrtsonis, Michael Michael, Evdoxia Hadjiharissi, Argiris Symeonidis, Eurydiki Michalis, Panagiotis Repoussis, Konstantinos Tsatalas, Anastasia Sioni, Zafiris Kartasis, Ekaterini Stefanoudaki, Michael Voulgarelis, Sosana Delimpasi, Dimitra Gika, Elissavet Vervesou, Konstantinos Konstantopoulos, Garyfalia Kokkini, Athanasios Zomas, Paraskevi Roussou, Nikolaos Anagnostopoulos, Theofanis Economopoulos, Evangelos Terpos, Konstantinos Zervas, Meletios A. DimopoulosClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article210.3816/clml.2011.n.028
33Rituximab and Subcutaneous 2-Chloro-2′-Deoxyadenosine as Therapy in Untreated and Relapsed Waldenström's MacroglobulinemiaD Laszlo, G Andreola, L Rigacci, A Fabbri, C Rabascio, A Pinto, M Negri, G MartinelliClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1710.3816/clml.2011.n.029
34Bendamustine Therapy in Patients With Relapsed or Refractory Waldenström's MacroglobulinemiaSteven P. Treon, Christina Hanzis, Christina Tripsas, Leukothea Ioakimidis, Christopher J. Patterson, Robert J. Manning, Patricia SheehyClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article9510.3816/clml.2011.n.030
35Factors Predicting Transformation of Asymptomatic IgM Monoclonal GammopathyAntonino Greco, Alessandra Tedeschi, Marzia Varettoni, Michele Nichelatti, Laura Paris, Francesca Ricci, Eleonora Vismara, Enrica MorraClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1010.3816/clml.2011.n.012
36Familial Plasma Cell Disorders and Associated CancersHenry T. Lynch, Carrie L. Snyder, Jane F. Lynch, Stephan ThoméClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article110.3816/clml.2011.n.013
37Familial Paraproteinemia: Hyper-Responsive B-Cells as EndophenotypeHelga M. Ögmundsdóttir, Hlíf Steingrímsdóttir, Vilhelmína HaraldsdóttirClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article710.3816/clml.2011.n.014
38What Causes Waldenström's Macroglobulinemia: Genetic or Immune-Related Factors, or a Combination?Sigurdur Y. Kristinsson, Ola LandgrenClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article710.3816/clml.2011.n.015
39Associated Malignancies in Patients with Waldenström's Macroglobulinemia and Their KinChristina Hanzis, Rohit P. Ojha, Zachary Hunter, Robert Manning, Megan Lewicki, Philip Brodsky, Leukothea Ioakimidis, Christina Tripsas, Christopher J. Patterson, Steven P. Treon, Patricia SheehyClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article4110.3816/clml.2011.n.016
40Differential Diagnosis of IgM MGUS and WM According to B-Lymphoid Infiltration by Morphology and Flow CytometryEnrique M. Ocio, Daniel del Carpio, Álvaro Caballero, Jennifer Alonso, Bruno Paiva, Roberto Pesoa, Teresa Villaescusa, Lucía López-Anglada, Belén Vidriales, Ramón García-SanzClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1210.3816/clml.2011.n.017
41Histone Deacetylase Inhibitors Demonstrate Significant Preclinical Activity as Single Agents, and in Combination with Bortezomib in Waldenström's MacroglobulinemiaJenny Y. Sun, Lian Xu, Hsuyi Tseng, Bryan Ciccarelli, Mariateresa Fulciniti, Zachary R. Hunter, Kaveh Maghsoudi, Evdoxia Hatjiharissi, Yangsheng Zhou, Guang Yang, Biao Zhu, Xia Liu, P Gong, Leukothea Ioakimidis, Patricia Sheehy, Christopher J. Patterson, Nikhil C. Munshi, Owen A. O'Connor, Steven P. TreonClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article2410.3816/clml.2011.n.036
42Pathogenesis and Morbidity of Autoantibody Syndromes in Waldenstrom's MacroglobulinemiaMarvin J. StoneClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article1610.3816/clml.2011.n.037
43Hepcidin Is Produced by Lymphoplasmacytic Cells and Is Associated With Anemia in Waldenström's MacroglobulinemiaBryan T. Ciccarelli, Christopher J. Patterson, Zachary R. Hunter, Christina Hanzis, Leukothea Ioakimidis, Robert Manning, Guang Yang, Lian Xu, Yangsheng Zhou, Jenny Sun, Xia Liu, Hsiuyi Tseng, Yang Cao, Patricia Sheehy, Scott J. Rodig, Steven P. TreonClinical Lymphoma Myeloma and Leukemia2011-022012-11-13 (updated: 2025-10-31)journal article3110.3816/clml.2011.n.038
44Prognostic Value of Reduced SMAD4 Expression in Patients With Metastatic Colorectal Cancer Under Oxaliplatin-Containing Chemotherapy: A Translational Study of the AIO Colorectal Study GroupAlexander Baraniskin, Johanna Munding, Karsten Schulmann, Dominik Meier, Rainer Porschen, Hendrik-Tobias Arkenau, Ullrich Graeven, Wolff Schmiegel, Andrea Tannapfel, Anke Reinacher-SchickClinical Colorectal Cancer2011-032012-11-09 (updated: 2025-10-26)journal article1210.3816/ccc.2011.n.003
45Upregulation of Glycogen Synthase Kinase 3β in Human Colorectal Adenocarcinomas Correlates With Accumulation of CTNNB1Hanlin L. Wang, John Hart, Lifang Fan, Reba Mustafi, Marc BissonnetteClinical Colorectal Cancer2011-032012-11-09 (updated: 2025-10-26)journal article1810.3816/ccc.2011.n.004
46Long-Term Outcome of Early-Stage Rectal Cancer Undergoing Standard Resection and Local ExcisionJunjie Peng, Wei Chen, Alan P. Venook, Weiqi Sheng, Ye Xu, Zuqing Guan, Guoxiang Cai, Sanjun CaiClinical Colorectal Cancer2011-032012-11-09 (updated: 2025-10-26)journal article1910.3816/ccc.2011.n.005
47Molecular Tests for Colorectal Cancer ScreeningLinda J.W. Bosch, Beatriz Carvalho, Remond J.A. Fijneman, Connie R. Jimenez, Herbert M. Pinedo, Manon van Engeland, Gerrit A. MeijerClinical Colorectal Cancer2011-032012-11-09 (updated: 2025-10-26)journal article7910.3816/ccc.2011.n.002
48Efficacy and Tolerability of Biweekly Bevacizumab, Irinotecan, Folinic Acid and Fluorouracil Intravenous Bolus (BIFF Regimen) in Patients With Metastatic Colorectal Cancer: The Southern Italy Cooperative Oncology Group ExperiencePasquale Comella, Bruno Massidda, Donato Natale, Carlo Putzu, Claudia Sandomenico, Gianfranco Filippelli, Sergio Palmeri, Giovanni Condemi, Giacomo Vessia, Giuseppe Barberis, Maria Teresa Ionta, Salvatore Tafuto, Enrico BarbatoClinical Colorectal Cancer2011-032012-11-09 (updated: 2025-10-26)journal article310.3816/ccc.2011.n.006
49Vascular and Metabolic Response to Bevacizumab-Containing Regimens in Two Patients With Colorectal Liver Metastases Measured by Dynamic Contrast-Enhanced MRI and Dynamic 18F-FDG-PETDennis Vriens, Lioe-Fee de Geus-Oei, Arend Heerschap, Hanneke W.M. van Laarhoven, Wim J.G. OyenClinical Colorectal Cancer2011-032012-11-09 (updated: 2025-10-26)journal article1510.3816/ccc.2011.n.010
50Correlation of Overall Survival With Gene Expression Profiles in a Prospective Study of Resectable Esophageal CancerSheela Rao, Lyndsey Welsh, David Cunningham, Robert H. te-Poele, Martin Benson, Andrew Norman, Claire Saffery, Ian Giddings, Paul Workman, Paul A. ClarkeClinical Colorectal Cancer2011-032012-11-09 (updated: 2025-10-26)journal article1110.3816/ccc.2011.n.007